Home › Forum Online Discussion › General › Missing link found between brain, immune system
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June 2, 2015 at 3:40 am #44439
http://www.sciencedaily.com/releases/2015/06/150601122445.htm
Structural and functional features of central nervous system lymphatic vessels
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14432.html~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
“In a stunning discovery that overturns decades of textbook teaching, researchers at the University of Virginia School of Medicine have determined that the brain is directly connected to the immune system by vessels previously thought not to exist. That such vessels could have escaped detection when the lymphatic system has been so thoroughly mapped throughout the body is surprising on its own, but the true significance of the discovery lies in the effects it could have on the study and treatment of neurological diseases ranging from autism to Alzheimer’s disease to multiple sclerosis.
“Instead of asking, ‘How do we study the immune response of the brain?’ ‘Why do multiple sclerosis patients have the immune attacks?’ now we can approach this mechanistically. Because the brain is like every other tissue connected to the peripheral immune system through meningeal lymphatic vessels,” said Jonathan Kipnis, PhD, professor in the UVA Department of Neuroscience and director of UVA’s Center for Brain Immunology and Glia (BIG). “It changes entirely the way we perceive the neuro-immune interaction. We always perceived it before as something esoteric that can’t be studied. But now we can ask mechanistic questions.”
“We believe that for every neurological disease that has an immune component to it, these vessels may play a major role,” Kipnis said. “Hard to imagine that these vessels would not be involved in a [neurological] disease with an immune component.”
New Discovery in Human Body
Kevin Lee, PhD, chairman of the UVA Department of Neuroscience, described his reaction to the discovery by Kipnis’ lab: “The first time these guys showed me the basic result, I just said one sentence: ‘They’ll have to change the textbooks.’ There has never been a lymphatic system for the central nervous system, and it was very clear from that first singular observation — and they’ve done many studies since then to bolster the finding — that it will fundamentally change the way people look at the central nervous system’s relationship with the immune system.”
Even Kipnis was skeptical initially. “I really did not believe there are structures in the body that we are not aware of. I thought the body was mapped,” he said. “I thought that these discoveries ended somewhere around the middle of the last century. But apparently they have not.”
‘Very Well Hidden’
The discovery was made possible by the work of Antoine Louveau, PhD, a postdoctoral fellow in Kipnis’ lab. The vessels were detected after Louveau developed a method to mount a mouse’s meninges — the membranes covering the brain — on a single slide so that they could be examined as a whole. “It was fairly easy, actually,” he said. “There was one trick: We fixed the meninges within the skullcap, so that the tissue is secured in its physiological condition, and then we dissected it. If we had done it the other way around, it wouldn’t have worked.”
After noticing vessel-like patterns in the distribution of immune cells on his slides, he tested for lymphatic vessels and there they were. The impossible existed. The soft-spoken Louveau recalled the moment: “I called Jony [Kipnis] to the microscope and I said, ‘I think we have something.'”
As to how the brain’s lymphatic vessels managed to escape notice all this time, Kipnis described them as “very well hidden” and noted that they follow a major blood vessel down into the sinuses, an area difficult to image. “It’s so close to the blood vessel, you just miss it,” he said. “If you don’t know what you’re after, you just miss it.”
“Live imaging of these vessels was crucial to demonstrate their function, and it would not be possible without collaboration with Tajie Harris,” Kipnis noted. Harris, a PhD, is an assistant professor of neuroscience and a member of the BIG center. Kipnis also saluted the “phenomenal” surgical skills of Igor Smirnov, a research associate in the Kipnis lab whose work was critical to the imaging success of the study.
Alzheimer’s, Autism, MS and Beyond
The unexpected presence of the lymphatic vessels raises a tremendous number of questions that now need answers, both about the workings of the brain and the diseases that plague it. For example, take Alzheimer’s disease. “In Alzheimer’s, there are accumulations of big protein chunks in the brain,” Kipnis said. “We think they may be accumulating in the brain because they’re not being efficiently removed by these vessels.” He noted that the vessels look different with age, so the role they play in aging is another avenue to explore. And there’s an enormous array of other neurological diseases, from autism to multiple sclerosis, that must be reconsidered in light of the presence of something science insisted did not exist.”
NATURE: Structural and functional features of central nervous system lympha
June 5, 2015 at 4:11 pm #44440June 10, 2015 at 3:54 am #44442June 10, 2015 at 5:42 pm #44444always permanent errata pointing in Finland, but these are Tao classic guru guru nodes?
true answers from yin yang gurus only, not insulters,
I do not remember pure land discussion of these guru nodesJune 10, 2015 at 5:56 pm #44446they get their hands on keys like a fat drunk
claim they are “guru guru”
no real answers on facts, only ulcerating fluff“relax relax” take your clothes off type material…
true Taoists know only history will tell
maybe Winn-Tao knows if nodes have true guru status…
they are not in classic emphasis..June 14, 2015 at 2:42 pm #44448Syncretism (/ˈsɪŋkrətɪzəm/) is the combining of different, often contradictory beliefs, while melding practices of various schools of thought. Syncretism involves the merger and analogizing of several originally discrete traditions, especially in the theology and mythology of religion, thus asserting an underlying unity and allowing for an inclusive approach to other faiths. Syncretism also occurs commonly in expressions of arts and culture (known as eclecticism) as well as politics (syncretic politics).
-https://en.wikipedia.org/wiki/SyncretismShugendō (修験道?) is a highly syncretic religion that originated in Heian Japan in which enlightenment is equated with attaining oneness with the kami (神?). This perception of experiential “awakening” is obtained through the understanding of the relationship between humanity and nature, centered on an ascetic, mountain-dwelling practice. The focus or goal of Shugendō is the development of spiritual experience and power. Having backgrounds in mountain worship, Shugendō incorporated beliefs or philosophies from early Japanese religious beliefs, Taoism and esoteric Buddhism arrived in Japan. The 7th century ascetic and mystic En no Gyōja is often considered as having first organized Shugendō as a doctrine. Shugendō literally means “the path of training and testing” or “the way to spiritual power through discipline.”
-https://en.wikipedia.org/wiki/Shugend%C5%8DWell many Taoists in the past have also studied Buddhist teachings and for some this is also useful in these conditions.
Also clearly those Indian lineages have at least as good if not even better meditation and energy yoga practices.
HOWDY
Ps. Sorry for my broken English.
June 14, 2015 at 3:33 pm #44450A catechism (pronunciation: /ˈkætəˌkizəm/; from Greek: κατηχέω, to teach orally), is a summary or exposition of doctrine and served as a learning introduction to the Sacraments traditionally used in catechesis, or Christian religious teaching of children and adult converts. Catechisms are doctrinal manuals – often in the form of questions followed by answers to be memorised – a format that has been used in non-religious or secular contexts as well. The term catechumen refers to the designated recipient of the catechetical work or instruction. In the Catholic Church, catachumens were usually placed separately during Holy Mass from those who received the Sacrament of Baptism.
-https://en.wikipedia.org/wiki/CatechismA comprehensive reference guide to the foundational Taoist practices taught by Master Mantak Chia
Organized by level and chi kung system for quick reference during practice or teaching
Includes 220 exercises from more than 20 of Master Chias practice systems, including the Inner Smile, the Six Healing Sounds, the Microcosmic Orbit, Chi Self-Massage, Cosmic Detox, and Iron Shirt Chi Kung
Covers all of the basic exercises in the Universal Taos first 6 levels of instruction
Organized progressively by level and system for quick reference during practice or teaching, this illustrated guide covers all of the foundational exercises in the Universal Healing Taos first 6 levels of instruction. Keyed to the corresponding book for each complete practice, such as Healing Light of the Tao and Chi Self-Massage, this guide includes 220 exercises from more than 20 of Master Mantak Chias practice systems, including the Inner Smile, the Six Healing Sounds, the Microcosmic Orbit, Iron Shirt Chi Kung, Wisdom Chi Kung, Tao Yin, Chi Nei Tsang, Cosmic Detox, Bone Marrow Nei Kung, Cosmic Healing, Tendon Nei Kung, and Karsai Nei Kung. Offering a comprehensive reference to the beginning and intermediate practices of the Universal Healing Tao, this book allows you to build a regular Taoist practice combining internal and external chi and sexual energy exercises from the full range of Master Chias teachings, enabling you to purify, transform, regenerate, and transcend not only your own energy but the energy around you as well.
June 14, 2015 at 6:24 pm #44452This brain and immune system work is really phenomenal but how do these Taoist cosmologies reconcile these profuse rodent origins with the supposed cosmic “prenatal” self? If it looks like a duck and quacks like one, is it not most likely a duck?
Both the primatomorphic and euarchontogliric origins of “humans” are rodential?
Both cousin and grandmother?Scientists Say This Rat Was Your Great-Great-Great-Great-(…)-Great-Great-
June 21, 2015 at 6:39 am #44454Deductive reasoning, also deductive logic or logical deduction or, informally, “top-down” logic, is the process of reasoning from one or more statements (premises) to reach a logically certain conclusion. It differs from inductive reasoning or abductive reasoning. Deductive reasoning links premises with conclusions. If all premises are true, the terms are clear, and the rules of deductive logic are followed, then the conclusion reached is necessarily true.
-https://en.wikipedia.org/wiki/Deductive_reasoningInductive reasoning (as opposed to deductive reasoning or abductive reasoning) is reasoning in which the premises seek to supply strong evidence for (not absolute proof of) the truth of the conclusion. While the conclusion of a deductive argument is certain, the truth of the conclusion of an inductive argument is probable, based upon the evidence given. The philosophical definition of inductive reasoning is more nuanced than simple progression from particular/individual instances to broader generalizations. Rather, the premises of an inductive logical argument indicate some degree of support (inductive probability) for the conclusion but do not entail it; that is, they suggest truth but do not ensure it. In this manner, there is the possibility of moving from general statements to individual instances (for example, statistical syllogisms, discussed below).
-https://en.wikipedia.org/wiki/Inductive_reasoningParampara (Sanskrit: परम्परा, paramparâ) denotes a succession of teachers and disciples in traditional Vedic culture and Indian religions such as Hinduism, Sikhism, Jainism and Buddhism. It is also known as guru-shishya tradition (“succession from guru to disciple”). The Sanskrit word literally means an uninterrupted row or series, order, succession, continuation, mediation, tradition. In the traditional residential form of education, the shishya remains with his or her guru as a family member and gets the education as a true learner.
-https://en.wikipedia.org/wiki/ParamparaIn this I personally would make some kind of compromise.
These ancient systems are immediately quite hopelessly chematic, clumsy and simple.
But because description and structure of the practices is so thoroughly entwined with the ancient conceptions, one really cannot throw away them too quickly.
I would continue to study both physics, mathematics etc. and also chosen ancient Chinese or Indian world view.
HOWDY
June 27, 2015 at 12:42 pm #44456Interesting would be if Mr. Yudelove would allow himself to be asked about the ‘Star in the Circle’ which he suggests as an alternative to Ba Gua, used in the Fusion practices, in ‘Taoist Yoga and Sexual Energy.’
-http://forum.healingdao.com/general/message/20337/Scientific literacy encompasses written, numerical, and digital literacy as they pertain to understanding science, its methodology, observations, and theories.
-https://en.wikipedia.org/wiki/Scientific_literacyFundamental interactions, also known as fundamental forces or interactive forces, are the interactions in physical systems that don’t appear to be reducible to more basic interactions. There are four conventionally accepted fundamental interactionsgravitational, electromagnetic, strong nuclear, and weak nuclear. Each one is understood as the dynamics of a field. The gravitational force is modeled as a continuous classical field. The other three are modeled as a discrete quantum field, and exhibit a measurable unit or elementary particle.
-https://en.wikipedia.org/wiki/Fundamental_interactionDerek Sears, professor of cosmochemistry at the University of Arkansas, explains:
planets are round because their gravitational field acts as though it originates from the center of the body and pulls everything toward it. With its large body and internal heating from radioactive elements, a planet behaves like a fluid, and over long periods of time succumbs to the gravitational pull from its center of gravity. The only way to get all the mass as close to planet’s center of gravity as possible is to form a sphere. The technical name for this process is “isostatic adjustment.” With much smaller bodies, such as the 20-kilometer asteroids we have seen in recent spacecraft images, the gravitational pull is too weak to overcome the asteroid’s mechanical strength. As a result, these bodies do not form spheres. Rather they maintain irregular, fragmentary shapes.
-http://www.scientificamerican.com/article/why-are-planets-round/A gravitational lens refers to a distribution of matter (such as a cluster of galaxies) between a distant source and an observer, that is capable of bending the light from the source, as it travels towards the observer. This effect is known as gravitational lensing and is one of the predictions of Albert Einstein’s general theory of relativity.
-https://en.wikipedia.org/wiki/Gravitational_lensThe Twin Quasar (Twin QSO or Double Quasar or Old Faithful, also known as SBS 0957+561, TXS 0957+561, Q0957+561 or QSO 0957+561 A/B), was discovered in 1979 and was the first identified gravitationally lensed object. It is a quasar that appears as two images, a result from gravitational lensing caused by the galaxy YGKOW G1 that is located in the line of sight between Earth and the quasar.
-https://en.wikipedia.org/wiki/Twin_QuasarThe principle of mandala is that it lives within a circle, thus any mandala that is visualized has to be represented within the symmetry of a circle. This is due to the fact that the circle is considered a primal form, and it is curious that even the earth on which we live is not flat but round or elliptical. The formation of mandala follows the same principle as that of light as expounded by scientific theory. Light waves move in a curve, thus bending space and forming an arc or curvature. The circular aura is an essential factor of the mandala and this is clearly evident in all the ancient tantric mandalas existing today.
-SWAMI SATYASANGANANDA SARASWATI, Tattwa ShuddhiSorry for my broken English.
This small book by this Bihar School of Yoga female swami (paramahamsa?) is quite interesting for it’s schematic representation of Samkhaya philosophy.
Though it’s far too repetitive.
Tattwa Shuddhi itself is advanced practice, because one would need to be very skillful both in (pranayama’s) kumbhaka and (pratyahara’s) trataka.
But what is very striking is how scientifically she is illiterate.
More or less any simple scientific example is somehow twisted.
Of course these Hindu spiritual names are bombastic, but she quite clearly don’t always live up to her sanskrit name if:
satyasangananda=happy-with-truth-without-speculation
HOWDY
https://www.youtube.com/watch?v=8i03pHirqbo (swamisatyasanganandasatsang)
June 27, 2015 at 2:49 pm #44458… claims that correlative thought was in some way unique to China have seriously impeded comparative studies; known by other names, correlative tendencies were no less prominent (and were sometimes more extreme) in premodfern India, the Middle East, the West, and Mesoamerica than in China….Our model pictures the growth of “high correlative” — multileveled reflecting cosmologies, nested hierarchies, abstract systems of correspondences, and similar developments — as byproducts of exegetical processes operarting in layered textual traditions over extended periods; the origins of primitive correlative thought and related animistic ideas seen at the earliest levels of those traditions, “worked up” abstractly in later strata, are tied in our model to neurobiological data.
-http://kairos.laetusinpraesens.org/corresp_0_h_6…how do these Taoist cosmologies reconcile these profuse rodent origins with the supposed cosmic “prenatal” self…
Book below is good introduction to ancient Chinese mindset, in my opinion, but one must admit that it’s also not very entertaining.
Also it would be useful to check Joseph Needham’s writings dealing with Chinese science and civilisation.
So one should go to nearest university which has many Needham’s books and see if one can find something both interesting and illuminating.
HOWDY
Ps. Sorry for my broken English.
http://www.amazon.com/Imperial-Guide-Feng-Chinese-Astrology/dp/B0091XM5GE
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